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Anti-SETDB1 Antibody Picoband®

Boster Bio Anti-SETDB1 Antibody Picoband® catalog # A00881-3. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

Synonyms

SETDB1; ESET; KIAA0067; KMT1E; Histone-lysine N-methyltransferase SETDB1; EC 2.1.1.-; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1

Gene Name

SETDB1

Gene ID

9869

UniProt

Q15047

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SETDB1 recombinant protein (Position: E20-E871) . Human SETDB1 shares 92.9% amino acid (aa) sequence identity with mouse SETDB1.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

143 kDa

Observed Molecular Weight

180 kDa

Applications Notes

6

Gene Name Synonym

SET domain bifurcated histone lysine methyltransferase 1

Protein Name

Histone-lysine N-methyltransferase SETDB1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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