Anti-SESN3 Antibody Picoband® HRP Conjugated
Product Specifications
Background
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Synonyms
SESN3; SEST3; Sestrin-3
Gene Name
SESN3
Gene ID
143686
UniProt
P58005
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SESN3 recombinant protein (Position: N13-H345) . Human SESN3 shares 92.5% amino acid (aa) sequence identity with mouse SESN3.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
57 kDa
Gene Name Synonym
Sestrin 3
Protein Name
Sestrin-3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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