Anti-NSDHL Antibody Picoband® HRP Conjugated
Product Specifications
Background
The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
Synonyms
NSDHL; H105E3; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; EC 1.1.1.170; Protein H105e3
Gene Name
NSDHL
Gene ID
50814
UniProt
Q15738
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NSDHL recombinant protein (Position: E7-K373) . Human NSDHL shares 83.4% and 87.3% amino acid (aa) sequence identity with mouse and rat NSDHL, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
42 kDa
Gene Name Synonym
NAD (P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL
Protein Name
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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