Anti-SERPING1/C1 Antibody Picoband® HRP Conjugated
Product Specifications
Background
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE) . Alternative splicing results in multiple transcript variants encoding the same isoform.
Synonyms
SERPING1; C1IN; C1NH; Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1
Gene Name
SERPING1
Gene ID
710
UniProt
P05155
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SERPING1/C1 recombinant protein (Position: S131-A500) . Human SERPING1/C1 shares 78.6% and 79.2% amino acid (aa) sequence identity with mouse and rat SERPING1/C1, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
55 kDa
Gene Name Synonym
Serpin family G member 1
Protein Name
Plasma protease C1 inhibitor
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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