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Anti-SERPING1/C1 Antibody Picoband® Biotin Conjugated

Product Specifications

Background

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE) . Alternative splicing results in multiple transcript variants encoding the same isoform.

Synonyms

SERPING1; C1IN; C1NH; Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1

Gene Name

SERPING1

Gene ID

710

UniProt

P05155

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SERPING1/C1 recombinant protein (Position: S131-A500) . Human SERPING1/C1 shares 78.6% and 79.2% amino acid (aa) sequence identity with mouse and rat SERPING1/C1, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

55 kDa

Gene Name Synonym

Serpin family G member 1

Protein Name

Plasma protease C1 inhibitor

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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