Anti-NMNAT1 Antibody Picoband® APC Conjugated
Product Specifications
Background
This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD) . The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.
Synonyms
NMNAT1; NMNAT; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; NMN/NaMN adenylyltransferase 1; EC 2.7.7.1; EC 2.7.7.18; Nicotinamide-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; Nicotinate-nucleotide adenylyltransferase 1; NaMN adenylyltransferase 1
Gene Name
NMNAT1
Gene ID
64802
UniProt
Q9HAN9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NMNAT1 recombinant protein (Position: K56-T279) . Human NMNAT1 shares 81.2% amino acid (aa) sequence identity with mouse NMNAT1.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
32 kDa
Applications Notes
6
Gene Name Synonym
Nicotinamide nucleotide adenylyltransferase 1
Protein Name
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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