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Anti-GUCY2D Antibody Picoband® Fluoro550 Conjugated

Selected Variant

A02625-1-Fluoro550

Size: 100 µg/Vial

Product Specifications

Background

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Synonyms

GUCY2D; CORD6; GUC1A4; GUC2D; RETGC; RETGC1; Retinal guanylyl cyclase 1; RETGC-1; EC 4.6.1.2; CG-E; Guanylate cyclase 2D, retinal; Rod outer segment membrane guanylate cyclase; ROS-GC

Gene Name

GUCY2D

Gene ID

3000

UniProt

Q02846

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human GUCY2D recombinant protein (Position: D65-S1103) .

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

120 kDa

Applications Notes

6

Gene Name Synonym

Guanylate cyclase 2D, retinal

Protein Name

Retinal guanylyl cyclase 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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