Anti-GUCY2D Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
Synonyms
GUCY2D; CORD6; GUC1A4; GUC2D; RETGC; RETGC1; Retinal guanylyl cyclase 1; RETGC-1; EC 4.6.1.2; CG-E; Guanylate cyclase 2D, retinal; Rod outer segment membrane guanylate cyclase; ROS-GC
Gene Name
GUCY2D
Gene ID
3000
UniProt
Q02846
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human GUCY2D recombinant protein (Position: D65-S1103) .
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
120 kDa
Applications Notes
6
Gene Name Synonym
Guanylate cyclase 2D, retinal
Protein Name
Retinal guanylyl cyclase 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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