Anti-GUCY2D Antibody Picoband®

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

GUCY2D; CORD6; GUC1A4; GUC2D; RETGC; RETGC1; Retinal guanylyl cyclase 1; RETGC-1; EC 4.6.1.2; CG-E; Guanylate cyclase 2D, retinal; Rod outer segment membrane guanylate cyclase; ROS-GC

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.