Anti-POLM Antibody Picoband® APC Conjugated
Product Specifications
Background
Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within B cell differentiation and somatic hypermutation of immunoglobulin genes. Predicted to be located in nucleoplasm. Predicted to be active in nucleus.
Synonyms
POLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; EC 2.7.7.7; Terminal transferase
Gene Name
POLM
Gene ID
27434
UniProt
Q9NP87
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human POLM recombinant protein (Position: E36-H481) . Human POLM shares 76.5% amino acid (aa) sequence identity with mouse POLM.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Aoufouchi, S., Flatter, E., Dahan, A., Faili, A., Bertocci, B., Storck, S., Delbos, F., Cocea, L., Gupta, N., Weill, J.-C., Reynaud, C.-A. Two novel human and mouse DNA polymerases of the polX family. Nucleic Acids Res. 28: 3684-3693, 2000. 2. Bertocci, B., De Smet, A., Berek, C., Weill, J.-C., Reynaud, C.-A. Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu. Immunity 19: 203-211, 2003. 3. Bertocci, B., De Smet, A., Flatter, E., Dahan, A., Bories, J.-C., Landreau, C., Weill, J.-C., Reynaud, C.-A. Cutting edge: DNA polymerase mu and lambda are dispensable for Ig gene hypermutation. J. Immun. 168: 3702-3706, 2002.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
55 kDa
Applications Notes
6
Gene Name Synonym
DNA polymerase mu
Protein Name
DNA-directed DNA/RNA polymerase mu
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
