Anti-PGAM5 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Enables GTPase activator activity and protein serine/threonine phosphatase activity. Involved in necroptotic process. Located in mitochondrial inner membrane.
Synonyms
PGAM5; Serine/threonine-protein phosphatase PGAM5, mitochondrial; EC 3.1.3.16; Bcl-XL-binding protein v68; Phosphoglycerate mutase family member 5
Gene Name
PGAM5
Gene ID
192111
UniProt
Q96HS1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PGAM5 recombinant protein (Position: D63-L252) . Human PGAM5 shares 95.3% and 93.7% amino acid (aa) sequence identity with mouse and rat PGAM5, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Hartz, P. A. Personal Communication. Baltimore, Md. 10/26/2012. 2. Lo, S.-C., Hannink, M. PGAM5, a Bcl-X-L-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex. J. Biol. Chem. 281: 37893-37903, 2006. 3. Sugawara, S., Kanamaru, Y., Sekine, S., Maekawa, L., Takahashi, A., Yamamoto, T., Watanabe, K., Fujisawa, T., Hattori, K., Ichijo, H. The mitochondrial protein PGAM5 suppresses energy consumption in brown adipocytes by repressing expression of uncoupling protein 1. J. Biol. Chem. 295: 5588-5601, 2020.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
32 kDa
Applications Notes
6
Gene Name Synonym
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
Protein Name
Serine/threonine-protein phosphatase PGAM5, mitochondrial
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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