Anti-PEX1 Antibody Picoband® APC Conjugated
Product Specifications
Background
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ubiquitin-modified protein reader activity. Predicted to be involved in establishment of protein localization to peroxisome; microtubule-based peroxisome localization; and protein unfolding. Located in peroxisome. Used to study Zellweger syndrome. Human ortholog (s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Orthologous to human PEX1 (peroxisomal biogenesis factor 1) .
Synonyms
Pex1; Peroxisome biogenesis factor 1; Peroxin-1
Gene Name
PEX1
Gene ID
71382
UniProt
Q5BL07
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived mouse PEX1 recombinant protein (Position: R25-A1284) . Mouse PEX1 shares 81.8% amino acid (aa) sequence identity with human PEX1.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Collins, C. S., Gould, S. J. Identification of a common PEX1 mutation in Zellweger syndrome. Hum. Mutat. 14: 45-53, 1999. 2. Crane, D. I., Maxwell, M. A., Paton, B. C. PEX1 mutations in the Zellweger spectrum of the peroxisome biogenesis disorders. Hum. Mutat. 26: 167-175, 2005. 3. Gartner, J., Moser, H., Valle, D. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. Nature Genet. 1: 16-23, 1992.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
143 kDa
Applications Notes
6
Gene Name Synonym
Peroxisomal biogenesis factor 1
Protein Name
Peroxisomal ATPase PEX1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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