Anti-PEX1 Antibody Picoband® Fluoro550 Conjugated
Selected Variant
A03025-1-Fluoro550
Size: 100 µg/Vial
Product Specifications
Background
This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene.
Synonyms
PEX1; Peroxisome biogenesis factor 1; Peroxin-1; Peroxisome biogenesis disorder protein 1
Gene Name
PEX1
Gene ID
5189
UniProt
O43933
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PEX1 recombinant protein (Position: Q256-R1266) . Human PEX1 shares 83.4% amino acid (aa) sequence identity with mouse PEX1.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Collins, C. S., Gould, S. J. Identification of a common PEX1 mutation in Zellweger syndrome. Hum. Mutat. 14: 45-53, 1999. 2. Crane, D. I., Maxwell, M. A., Paton, B. C. PEX1 mutations in the Zellweger spectrum of the peroxisome biogenesis disorders. Hum. Mutat. 26: 167-175, 2005. 3. Gartner, J., Moser, H., Valle, D. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. Nature Genet. 1: 16-23, 1992.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
143 kDa
Applications Notes
6
Gene Name Synonym
Peroxisomal biogenesis factor 1
Protein Name
Peroxisomal ATPase PEX1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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