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Anti-PDZD8 Antibody Picoband® APC Conjugated

Product Specifications

Background

Predicted to enable lipid binding activity and zinc ion binding activity. Involved in several processes, including mitochondrial calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and regulation of cell morphogenesis. Located in endoplasmic reticulum membrane and mitochondria-associated endoplasmic reticulum membrane contact site.

Synonyms

PDZD8; PDZK8; PDZ domain-containing protein 8; Sarcoma antigen NY-SAR-84/NY-SAR-104

Gene Name

PDZD8

Gene ID

118987

UniProt

Q8NEN9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PDZD8 recombinant protein (Position: R28-D1146) . Human PDZD8 shares 86.4% amino acid (aa) sequence identity with mouse PDZD8.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Al-Amri, A. H., Armstrong, P., Amici, M., Ligneul, C., Rouse, J., El-Asrag, M. E., Pantiru, A., Vancollie, V. E., Ng, H. W. Y., Ogbeta, J. A., Goodchild, K., Ellegood, J., and 13 others. PDZD8 disruption causes cognitive impairment in humans, mice, and fruit flies. Biol. Psychiat. 92: 323-334, 2022. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/20/2011. 3. Henning, M. S., Morham, S. G., Goff, S. P., Naghavi, M. H. PDZD8 is a novel Gag-interacting factor that promotes retroviral infection. J. Virol. 84: 8990-8995, 2010.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

129 kDa

Applications Notes

6

Gene Name Synonym

PDZ domain containing 8

Protein Name

PDZ domain-containing protein 8

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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