Anti-PDZD8 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Predicted to enable lipid binding activity and zinc ion binding activity. Involved in several processes, including mitochondrial calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and regulation of cell morphogenesis. Located in endoplasmic reticulum membrane and mitochondria-associated endoplasmic reticulum membrane contact site.
Synonyms
PDZD8; PDZK8; PDZ domain-containing protein 8; Sarcoma antigen NY-SAR-84/NY-SAR-104
Gene Name
PDZD8
Gene ID
118987
UniProt
Q8NEN9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PDZD8 recombinant protein (Position: R28-D1146) . Human PDZD8 shares 86.4% amino acid (aa) sequence identity with mouse PDZD8.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Al-Amri, A. H., Armstrong, P., Amici, M., Ligneul, C., Rouse, J., El-Asrag, M. E., Pantiru, A., Vancollie, V. E., Ng, H. W. Y., Ogbeta, J. A., Goodchild, K., Ellegood, J., and 13 others. PDZD8 disruption causes cognitive impairment in humans, mice, and fruit flies. Biol. Psychiat. 92: 323-334, 2022. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/20/2011. 3. Henning, M. S., Morham, S. G., Goff, S. P., Naghavi, M. H. PDZD8 is a novel Gag-interacting factor that promotes retroviral infection. J. Virol. 84: 8990-8995, 2010.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
129 kDa
Gene Name Synonym
PDZ domain containing 8
Protein Name
PDZ domain-containing protein 8
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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