Anti-NAV1 Antibody Picoband® PE Conjugated
Product Specifications
Background
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants.
Synonyms
NAV1; KIAA1151; KIAA1213; POMFIL3; STEERIN1; Neuron navigator 1; Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1
Gene Name
NAV1
Gene ID
89796
UniProt
Q8NEY1
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NAV1 recombinant protein (Position: Q250-H1813) . Human NAV1 shares 97.1% amino acid (aa) sequence identity with mouse NAV1.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Coy, J. F., Wiemann, S., Bechmann, I., Bachner, D., Nitsch, R., Kretz, O., Christiansen, H., Poustka, A. Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene 290: 73-94, 2002. 2. Hirosawa, M., Nagase, T., Ishikawa, K., Kikuno, R., Nomura, N., Ohara, O. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. DNA Res. 6: 329-336, 1999. 3. Maes, T., Barcelo, A., Buesa, C. Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans. Genomics 80: 21-30, 2002.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
202 kDa
Applications Notes
6
Gene Name Synonym
Neuron navigator 1
Protein Name
Neuron navigator 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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