Anti-ENTPD5 Antibody Picoband® APC Conjugated

The protein encoded by this gene is similar to E-type nucleotidases (NTPases) /ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.

ENTPD5; CD39L4; PCPH; Ectonucleoside triphosphate diphosphohydrolase 5; NTPDase 5; EC 3.6.1.6; CD39 antigen-like 4; ER-UDPase; Guanosine-diphosphatase ENTPD5; GDPase ENTPD5; EC 3.6.1.42; Nucleoside diphosphatase; Uridine-diphosphatase ENTPD5; UDPase ENTPD5

E.coli-derived human ENTPD5 recombinant protein (Position: D95-H428) . Human ENTPD5 shares 90.1% and 88.9% amino acid (aa) sequence identity with mouse and rat ENTPD5, respectively.

1. Chadwick, B. P., Frischauf, A.-M. The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster. Genomics 50: 357-367, 1998. 2. Chadwick, B. P., Williamson, J., Sheer, D., Frischauf, A.-M. cDNA cloning and chromosomal mapping of a mouse gene with homology to NTPases. Mammalian Genome 9: 162-164, 1998. 3. Fang, M., Shen, Z., Huang, S., Zhao, L., Chen, S., Mak, T. W., Wang, X. The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell 143: 711-724, 2010.