Anti-CXXC5 Antibody Picoband® HRP Conjugated

The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regulates cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene.

CXXC5; HSPC195; TCCCIA00297; CXXC-type zinc finger protein 5; CF5; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF

A synthetic peptide corresponding to a sequence in the middle region of human CXXC5. Human CXXC5 shares 100% amino acid (aa) sequence identity with both mouse and rat CXXC5.

1. Andersson, T., Sodersten, E., Duckworth, J. K., Cascante, A., Fritz, N., Sacchetti, P., Cervenka, I., Bryja, V., Hermanson, O. CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. J. Biol. Chem. 284: 3672-3681, 2009. 2. Aras, S., Pak, O., Sommer, N., Finley Jr., R., Huttemann, M., Weissmann, N., Grossman, L. I. Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5, and CHCHD2. Nucleic Acids Res. 41: 2255-2266, 2013. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 4/22/2009.