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Anti-CXXC5 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regulates cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene.

Synonyms

CXXC5; HSPC195; TCCCIA00297; CXXC-type zinc finger protein 5; CF5; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF

Gene Name

CXXC5

Gene ID

51523

UniProt

Q7LFL8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human CXXC5. Human CXXC5 shares 100% amino acid (aa) sequence identity with both mouse and rat CXXC5.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Andersson, T., Sodersten, E., Duckworth, J. K., Cascante, A., Fritz, N., Sacchetti, P., Cervenka, I., Bryja, V., Hermanson, O. CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. J. Biol. Chem. 284: 3672-3681, 2009. 2. Aras, S., Pak, O., Sommer, N., Finley Jr., R., Huttemann, M., Weissmann, N., Grossman, L. I. Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5, and CHCHD2. Nucleic Acids Res. 41: 2255-2266, 2013. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 4/22/2009.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06865-1-Fluoro488

Calculated Molecular Weight

33 kDa

Applications Notes

6

Gene Name Synonym

CXXC finger protein 5

Protein Name

CXXC-type zinc finger protein 5

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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