Anti-CXXC5 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regulates cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene.
Synonyms
CXXC5; HSPC195; TCCCIA00297; CXXC-type zinc finger protein 5; CF5; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF
Gene Name
CXXC5
Gene ID
51523
UniProt
Q7LFL8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human CXXC5. Human CXXC5 shares 100% amino acid (aa) sequence identity with both mouse and rat CXXC5.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Andersson, T., Sodersten, E., Duckworth, J. K., Cascante, A., Fritz, N., Sacchetti, P., Cervenka, I., Bryja, V., Hermanson, O. CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. J. Biol. Chem. 284: 3672-3681, 2009. 2. Aras, S., Pak, O., Sommer, N., Finley Jr., R., Huttemann, M., Weissmann, N., Grossman, L. I. Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5, and CHCHD2. Nucleic Acids Res. 41: 2255-2266, 2013. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 4/22/2009.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
33 kDa
Gene Name Synonym
CXXC finger protein 5
Protein Name
CXXC-type zinc finger protein 5
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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