Anti-TAF3 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]) .
Synonyms
TAF3; Transcription initiation factor TFIID subunit 3; 140 kDa TATA box-binding protein-associated factor; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; TAF (II140; TAF140; TAFII-140; TAFII140
Gene Name
TAF3
Gene ID
83860
UniProt
Q5VWG9
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human TAF3 recombinant protein (Position: M1-E612) . Human TAF3 shares 86.2% amino acid (aa) sequence identity with mouse TAF3.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Gangloff, Y.-G., Pointud, J.-C., Thuault, S., Carre, L., Romier, C., Muratoglu, S., Brand, M., Tora, L., Couderc, J.-L., Davidson, I. The TFIID components human TAF (II) 140 and Drosophila BIP2 (TAF (II) 155) are novel metazoan homologues of yeast TAF (II) 47 containing a histone fold and a PHD finger. Molec. Cell. Biol. 21: 5109-5121, 2001. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 9/21/2012. 3. Liu, Z., Scannell, D. R., Eisen, M. B., Tjian, R. Control of embryonic stell cell lineage commitment by core promoter factor, TAF3. Cell 146: 720-731, 2011.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
104 kDa
Gene Name Synonym
TATA-box binding protein associated factor 3
Protein Name
Transcription initiation factor TFIID subunit 3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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