Anti-SUN5 Antibody Picoband® APC Conjugated

The protein encoded by this gene appears to play a role in the meiotic stage of spermatogenesis. The encoded protein localizes to the junction between the sperm head and body and may be involved in nuclear envelope reconstitution and nuclear migration. Mutations in this gene have been implicated in acephalic spermatozoa syndrome.

SUN5; SPAG4L; TSARG4; SUN domain-containing protein 5; Sad1 and UNC84 domain-containing protein 5; Sperm-associated antigen 4-like protein; Testis and spermatogenesis-related gene 4 protein

1. Razafsky, D., Hodzic, D. Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections. J. Cell Biol. 186: 461-472, 2009. 2. Xing, X.-W., Li, L.-Y., Fu, J.-J., Zhu, W.-B., Liu, G., Liu, S.-F., Lu, G.-X. Cloning of cDNA of TSARG4, a human spermatogenesis related gene. Acta Biochim. Biophys. Sinica 35: 283-288, 2003. 3. Yassine, S., Escoffier, J., Abi Nahed, R., Pierre, V., Karaouzene, T., Ray, P. F., Arnoult, C. Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope. PLoS One 10: e0118698, 2015. Note: Electronic Article. Erratum: PLoS One 10: e0125452, 2015.