Anti-SUN5 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
The protein encoded by this gene appears to play a role in the meiotic stage of spermatogenesis. The encoded protein localizes to the junction between the sperm head and body and may be involved in nuclear envelope reconstitution and nuclear migration. Mutations in this gene have been implicated in acephalic spermatozoa syndrome.
Synonyms
SUN5; SPAG4L; TSARG4; SUN domain-containing protein 5; Sad1 and UNC84 domain-containing protein 5; Sperm-associated antigen 4-like protein; Testis and spermatogenesis-related gene 4 protein
Gene Name
SUN5
Gene ID
140732
UniProt
Q8TC36
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SUN5 recombinant protein (Position: E16-K341) . Human SUN5 shares 79.1% amino acid (aa) sequence identity with mouse SUN5.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Razafsky, D., Hodzic, D. Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections. J. Cell Biol. 186: 461-472, 2009. 2. Xing, X.-W., Li, L.-Y., Fu, J.-J., Zhu, W.-B., Liu, G., Liu, S.-F., Lu, G.-X. Cloning of cDNA of TSARG4, a human spermatogenesis related gene. Acta Biochim. Biophys. Sinica 35: 283-288, 2003. 3. Yassine, S., Escoffier, J., Abi Nahed, R., Pierre, V., Karaouzene, T., Ray, P. F., Arnoult, C. Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope. PLoS One 10: e0118698, 2015. Note: Electronic Article. Erratum: PLoS One 10: e0125452, 2015.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
43 kDa
Gene Name Synonym
Sad1 and UNC84 domain containing 5
Protein Name
SUN domain-containing protein 5
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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