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Anti-SUN1 Antibody Picoband® APC Conjugated

Product Specifications

Background

This gene is a member of the unc-84 homolog family and encodes a nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described.

Synonyms

SUN1; KIAA0810; UNC84A; SUN domain-containing protein 1; Protein unc-84 homolog A; Sad1/unc-84 protein-like 1

Gene Name

SUN1

Gene ID

23353

UniProt

O94901

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SUN1 recombinant protein (Position: D32-E619) . Human SUN1 shares 62.6% amino acid (aa) sequence identity with mouse SUN1.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Bray, J. D., Chennathukuzhi, V. M., Hecht, N. B. Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. Genomics 79: 799-808, 2002. 2. Chen, C.-Y., Chi, Y.-H., Mutalif, R. A., Starost, M. F., Myers, T. G., Anderson, S. A., Stewart, C. L., Jeang, K.-T. Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies. Cell 149: 565-577, 2012. 3. Ding, X., Xu, R., Yu, J., Xu, T., Zhuang, Y., Han, M. SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev. Cell 12: 863-872, 2007.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

87 kDa

Applications Notes

6

Gene Name Synonym

Sad1 and UNC84 domain containing 1

Protein Name

SUN domain-containing protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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