Anti-SUN1 Antibody Picoband® Biotin Conjugated

This gene is a member of the unc-84 homolog family and encodes a nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described.

1. Bray, J. D., Chennathukuzhi, V. M., Hecht, N. B. Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. Genomics 79: 799-808, 2002. 2. Chen, C.-Y., Chi, Y.-H., Mutalif, R. A., Starost, M. F., Myers, T. G., Anderson, S. A., Stewart, C. L., Jeang, K.-T. Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies. Cell 149: 565-577, 2012. 3. Ding, X., Xu, R., Yu, J., Xu, T., Zhuang, Y., Han, M. SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev. Cell 12: 863-872, 2007.