Anti-SUN1 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene is a member of the unc-84 homolog family and encodes a nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described.
Synonyms
SUN1; KIAA0810; UNC84A; SUN domain-containing protein 1; Protein unc-84 homolog A; Sad1/unc-84 protein-like 1
Gene Name
SUN1
Gene ID
23353
UniProt
O94901
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human SUN1 recombinant protein (Position: D32-E619) . Human SUN1 shares 62.6% amino acid (aa) sequence identity with mouse SUN1.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Bray, J. D., Chennathukuzhi, V. M., Hecht, N. B. Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. Genomics 79: 799-808, 2002. 2. Chen, C.-Y., Chi, Y.-H., Mutalif, R. A., Starost, M. F., Myers, T. G., Anderson, S. A., Stewart, C. L., Jeang, K.-T. Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies. Cell 149: 565-577, 2012. 3. Ding, X., Xu, R., Yu, J., Xu, T., Zhuang, Y., Han, M. SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev. Cell 12: 863-872, 2007.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
87 kDa
Gene Name Synonym
Sad1 and UNC84 domain containing 1
Protein Name
SUN domain-containing protein 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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