Anti-STXBP3 Antibody Picoband® HRP Conjugated
Product Specifications
Background
Enables syntaxin binding activity. Involved in negative regulation of calcium ion-dependent exocytosis; neutrophil degranulation; and platelet aggregation. Located in cytosol; plasma membrane; and secretory granule.
Synonyms
STXBP3; Syntaxin-binding protein 3; Platelet Sec1 protein; PSP; Protein unc-18 homolog 3; Unc18-3; Protein unc-18 homolog C; Unc-18C
Gene Name
STXBP3
Gene ID
6814
UniProt
O00186
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human STXBP3 recombinant protein (Position: E7-E592) . Human STXBP3 shares 91.8% amino acid (aa) sequence identity with mouse STXBP3.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Gengyo-Ando, K., Kitayama, H., Mukaida, M., Ikawa, Y. A murine neural-specific homolog corrects cholinergic defects in Caenorhabditis elegans unc-18 mutants. J. Neurosci. 16: 6695-6702, 1996. 2. Kanda, H., Tamori, Y., Shinoda, H., Yoshikawa, M., Sakaue, M., Udagawa, J., Otani, H., Tashiro, F., Miyazaki, J., Kasuga, M. Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization. J. Clin. Invest. 115: 291-301, 2005. 3. Reed, G. L., Houng, A. K., Fitzgerald, M. L. Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion. Blood 93: 2617-2626, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
68 kDa
Gene Name Synonym
Syntaxin binding protein 3
Protein Name
Syntaxin-binding protein 3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.
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