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Anti-NEK5 Antibody Picoband® Biotin Conjugated

Product Specifications

Background

Enables protein kinase activity. Acts upstream of or within positive regulation of striated muscle cell differentiation. Predicted to be located in sperm flagellum. Is expressed in choroid invagination; diencephalon roof plate; medulla oblongata part of 4th ventricle choroid plexus; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human NEK5 (NIMA related kinase 5) .

Synonyms

Nek5; Serine/threonine-protein kinase Nek5; EC 2.7.11.1; Never in mitosis A-related kinase 5; NimA-related protein kinase 5

Gene Name

NEK5

Gene ID

330721

UniProt

Q7TSC3

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived mouse NEK5 recombinant protein (Position: K22-Q627) . Mouse NEK5 shares 80.8% amino acid (aa) sequence identity with human NEK5.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 1/8/2016. 2. Melo Hanchuk, T. D., Papa, P. F., La Guardia, P. G., Vercesi, A. E., Kobarg, J. Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration. Cell. Signal. 27: 1168-1177, 2015. 3. Oakley, B. R., Morris, N. R. A mutation in Aspergillus nidulans that blocks the transition from interphase to prophase. J. Cell. Biol. 96: 1155-1158, 1983.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

81 kDa

Gene Name Synonym

NIMA (never in mitosis gene a) -related expressed kinase 5

Protein Name

Serine/threonine-protein kinase Nek5

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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