Anti-NEK9 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein is activated in mitosis and, in turn, activates other family members during mitosis. This protein also mediates cellular processes that are essential for interphase progression.
Synonyms
NEK9; KIAA1995; NEK8; NERCC; Serine/threonine-protein kinase Nek9; EC 2.7.11.1; Nercc1 kinase; Never in mitosis A-related kinase 9; NimA-related protein kinase 9; NimA-related kinase 8; Nek8
Gene Name
NEK9
Gene ID
91754
UniProt
Q8TD19
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NEK9 recombinant protein (Position: K81-K945) . Human NEK9 shares 94.8% amino acid (aa) sequence identity with mouse NEK9.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Belham, C., Roig, J., Caldwell, J. A., Aoyama, Y., Kemp, B. E., Comb, M., Avruch, J. A mitotic cascade of NIMA family kinases: Nercc1/Nek9 activates the Nek6 and Nek7 kinases. J. Biol. Chem. 278: 34897-34909, 2003. 2. Casey, J. P., Brennan, K., Scheidel, N., McGettigan, P., Lavin, P. T., Carter, S., Ennis, S., Dorkins, H., Ghali, N., Blacque, O. E., McGee, M. M., Murphy, H., Lynch, S. A. Recessive NEK9 mutation causes a lethal skeletal dysplasia with evidence of cell cycle and ciliary defects. Hum. Molec. Genet. 25: 1824-1835, 2016. 3. Holland, P. M., Milne, A., Garka, K., Johnson, R. S., Willis, C., Sims, J. E., Rauch, C. T., Bird, T. A., Virca, G. D. Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2. J. Biol. Chem. 277: 16229-16240, 2002.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
107 kDa
Gene Name Synonym
NIMA related kinase 9
Protein Name
Serine/threonine-protein kinase Nek9
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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