Anti-MYBBP1A Antibody Picoband® Cy3 Conjugated

Enables E-box binding activity and transcription corepressor activity. Involved in circadian regulation of gene expression and negative regulation of DNA-templated transcription. Acts upstream of or within respiratory electron transport chain. Located in cytoplasm and nucleolus. Part of NLS-dependent protein nuclear import complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb. Orthologous to human MYBBP1A (MYB binding protein 1a) .

E.coli-derived mouse MYBBP1A recombinant protein (Position: D39-R1316) . Mouse MYBBP1A shares 69.7% and 89% amino acid (aa) sequence identity with human and rat MYBBP1A, respectively.

1. Favier, D., Gonda, T. J. Detection of proteins that bind to the leucine zipper motif of c-Myb. Oncogene 9: 305-311, 1994. 2. Keough, R., Woollatt, E., Crawford, J., Sutherland, G. R., Plummer, S., Casey, G., Gonda, T. J. Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3. Genomics 62: 483-489, 1999. 3. Mori, S., Bernardi, R., Laurent, A., Resnati, M., Crippa, A., Gabrieli, A., Keough, R., Gonda, T. J., Blasi, F. Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor. PLoS One 7: e39723, 2012.