Anti-PARP16 Antibody Fluoro488 Conjugated
Product Specifications
Background
Enables kinase binding activity; pentosyltransferase activity; and protein serine/threonine kinase activator activity. Involved in IRE1-mediated unfolded protein response; negative regulation of cytoplasmic translation; and protein auto-ADP-ribosylation. Located in endoplasmic reticulum tubular network and nuclear envelope.
Synonyms
PARP16; ARTD15; C15orf30; Protein mono-ADP-ribosyltransferase PARP16; EC 2.4.2.-; ADP-ribosyltransferase diphtheria toxin-like 15; Poly [ADP-ribose] polymerase 16; PARP-16
Gene Name
PARP16
Gene ID
54956
UniProt
Q8N5Y8
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PARP16 recombinant protein (Position: A9-Y254) . Human PARP16 shares 92.3% and 90.2% amino acid (aa) sequence identity with mouse and rat PARP16, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Di Paola, S., Micaroni, M., Di Tullio, G., Buccione, R., Di Girolamo, M. PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-beta-1. PLoS One 7: e37352, 2012. 2. Gross, M. B. Personal Communication. Baltimore, Md. 4/20/2023. 3. Jwa, M., Chang, P. PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1-alpha-mediated unfolded protein response. Nature Cell Biol. 14: 1223-1230, 2012. Note: Erratum: Nature Cell Biol. 15: 123 only, 2013.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Poly (ADP-ribose) polymerase family member 16
Protein Name
Protein mono-ADP-ribosyltransferase PARP16
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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