Anti-NLRP6 Antibody Picoband® APC Conjugated

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

E.coli-derived human NLRP6 recombinant protein (Position: R14-E887) . Human NLRP6 shares 71.7% and 72.9% amino acid (aa) sequence identity with mouse and rat NLRP6, respectively.

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