LDHA-IN-3
LDHA-IN-3 (compound 2), as a selenobenzene compound, is a potent, noncompetitive lactate dehydrogenase (LDHA) inhibitor (IC50=145.2 nM) . LDHA-IN-3 can be used for the research of cancer[1].
Product Specifications
CAS Number
[227010-33-5]
UNSPSC
12352005
Target
Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ldha-in-3.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(C1=CC=C([Se]C2=CC=CC=C2)C=C1)(F)F
Molecular Formula
C13H9F3Se
Molecular Weight
301.17
References & Citations
[1]Kim EY, et al. A Novel Lactate Dehydrogenase Inhibitor, 1- (Phenylseleno) -4- (Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death. Sci Rep. 2019;9 (1) :3969. Published 2019 Mar 8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LDHA
Available Sizes
Curated Selection
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