LDHA-IN-3

LDHA-IN-3 (compound 2), as a selenobenzene compound, is a potent, noncompetitive lactate dehydrogenase (LDHA) inhibitor (IC50=145.2 nM) . LDHA-IN-3 can be used for the research of cancer[1].

Product Specifications

CAS Number

[227010-33-5]

UNSPSC

12352005

Target

Lactate Dehydrogenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ldha-in-3.html

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(C1=CC=C([Se]C2=CC=CC=C2)C=C1)(F)F

Molecular Formula

C13H9F3Se

Molecular Weight

301.17

References & Citations

[1]Kim EY, et al. A Novel Lactate Dehydrogenase Inhibitor, 1- (Phenylseleno) -4- (Trifluoromethyl) Benzene, Suppresses Tumor Growth through Apoptotic Cell Death. Sci Rep. 2019;9 (1) :3969. Published 2019 Mar 8.