Anti-MSTO1 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Involved in mitochondrion distribution; mitochondrion organization; and positive regulation of mitochondrial fusion. Located in mitochondrial outer membrane. Is active in cytosol.
Synonyms
MSTO1; LST005; SLTP005; Protein misato homolog 1
Gene Name
MSTO1
Gene ID
55154
UniProt
Q9BUK6
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human MSTO1 recombinant protein (Position: E44-Q518) . Human MSTO1 shares 78.1% amino acid (aa) sequence identity with mouse MSTO1.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Donkervoort, S., Sabouny, R., Yun, P., Gauquelin, L., Chao, K. R., Hu, Y., Al Khatib, I., Topf, A., Mohassel, P., Cummings, B. B., Kaur, R., Saade, D., and 37 others. MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement. Acta Neuropath. 138: 1013-1031, 2019. 2. Gal, A., Balicza, P., Weaver, D., Naghdi, S., Joseph, S. K., Varnai, P., Gyuris, T., Horvath, A., Nagy, L., Seifert, E. L., Molnar, J. J., Hajnoczky, G. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans. EMBO Molec. Med. 9: 967-984, 2017. Note: Erratum: 15: e17911, 2023. 3. Gal, A., Balicza, P., Weaver, D., Naghdi, S., Joseph, S. K., Varnai, P., Gyuris, T., Horvath, A., Nagy, L., Seifert, E. L., Molnar, M. J., Hajnoczky, G. MSTO1 is a cytoplasmic pro-mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans. EMBO Molec. Med. 15: e17911, 2023. Note: Erratum.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
62 kDa
Gene Name Synonym
Misato mitochondrial distribution and morphology regulator 1
Protein Name
Protein misato homolog 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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