Anti-MAML3 Antibody Picoband® APC Conjugated

Enables transcription coactivator activity. Involved in Notch signaling pathway and positive regulation of transcription by RNA polymerase II. Located in nuclear speck.

1. Lin, S.-E., Oyama, T., Nagase, T., Harigaya, K., Kitagawa, M. Identification of new human Mastermind proteins defines a family that consists of positive regulators for Notch signaling. J. Biol. Chem. 277: 50612-50620, 2002. 2. Nagase, T., Nakayama, M., Nakajima, D., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 8: 85-95, 2001. 3. Wu, L., Sun, T., Kobayashi, K., Gao, P., Griffin, J. D. Identification of a family of mastermind-like transcriptional coactivators for mammalian Notch receptors. Molec. Cell. Biol. 22: 7688-7700, 2002.