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Anti-CBX6 Antibody Picoband® HRP Conjugated

Product Specifications

Background

Predicted to enable chromatin binding activity and methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of PcG protein complex. Biomarker of glioblastoma.

Synonyms

CBX6; Chromobox protein homolog 6

Gene Name

CBX6

Gene ID

23466

UniProt

O95503

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human CBX6 recombinant protein (Position: D50-K236) . Human CBX6 shares 96.3% amino acid (aa) sequence identity with mouse CBX6.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 4/18/2017. 2. Morey, L., Pascual, G., Cozzuto, L., Roma, G., Wutz, A., Benitah, S. A. Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell 10: 47-62, 2012. 3. Vincenz, C., Kerppola, T. K. Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences. Proc. Nat. Acad. Sci. 105: 16572-16577, 2008.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

44 kDa

Gene Name Synonym

Chromobox 6

Protein Name

Chromobox protein homolog 6

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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