Anti-CBX6 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Predicted to enable chromatin binding activity and methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of PcG protein complex. Biomarker of glioblastoma.
Synonyms
CBX6; Chromobox protein homolog 6
Gene Name
CBX6
Gene ID
23466
UniProt
O95503
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human CBX6 recombinant protein (Position: D50-K236) . Human CBX6 shares 96.3% amino acid (aa) sequence identity with mouse CBX6.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Hartz, P. A. Personal Communication. Baltimore, Md. 4/18/2017. 2. Morey, L., Pascual, G., Cozzuto, L., Roma, G., Wutz, A., Benitah, S. A. Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell 10: 47-62, 2012. 3. Vincenz, C., Kerppola, T. K. Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences. Proc. Nat. Acad. Sci. 105: 16572-16577, 2008.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
44 kDa
Gene Name Synonym
Chromobox 6
Protein Name
Chromobox protein homolog 6
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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