Anti-PCYT2 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants.
Synonyms
PCYT2; Ethanolamine-phosphate cytidylyltransferase; EC 2.7.7.14; CTP:phosphoethanolamine cytidylyltransferase; Phosphorylethanolamine transferase
Gene Name
PCYT2
Gene ID
5833
UniProt
Q99447
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PCYT2 recombinant protein (Position: D32-F389) . Human PCYT2 shares 89.5% and 94.4% amino acid (aa) sequence identity with mouse and rat PCYT2, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Christen, M., Oevermann, A., Rupp, S., Vaz, F. M., Wever, E. J. M., Braus, B. K., Jagannathan, V., Kehl, A., Hytonen, M. K., Lohi, H., Leeb, T. PCYT2 deficiency in Saarlooswolfdogs with progressive retinal, central, and peripheral neurodegeneration. Molec. Genet. Metab. 141: 108149, 2024. 2. Fullerton, M. D., Hakimuddin, F., Bakovic, M. Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2) . Molec. Cell Biol. 27: 3327-3336, 2007. 3. Kaiyrzhanov, R., Wortmann, S., Reid, T., Dehghani, M., Vahidi Mehrjardi, M. Y., Alhaddad, B., Wagner, M., Deschauer, M., Cordts, I., Fernandez-Murray, J. P., Treffer, V., Metanat, Z., Pittman, A., Houlden, H., Meitinger, T., Carroll, C., McMaster, C. R., Maroofian, R. Defective phosphatidylethanolamine biosynthesis leads to a broad ataxia-spasticity spectrum. Brain 144: e30, 2021. Note: Erratum: Brain 144: e52, 2021.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
44 kDa
Gene Name Synonym
Phosphate cytidylyltransferase 2, ethanolamine
Protein Name
Ethanolamine-phosphate cytidylyltransferase
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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