Anti-PCYT2 Antibody Picoband®

This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants.

E.coli-derived human PCYT2 recombinant protein (Position: D32-F389) . Human PCYT2 shares 89.5% and 94.4% amino acid (aa) sequence identity with mouse and rat PCYT2, respectively.

1. Christen, M., Oevermann, A., Rupp, S., Vaz, F. M., Wever, E. J. M., Braus, B. K., Jagannathan, V., Kehl, A., Hytonen, M. K., Lohi, H., Leeb, T. PCYT2 deficiency in Saarlooswolfdogs with progressive retinal, central, and peripheral neurodegeneration. Molec. Genet. Metab. 141: 108149, 2024. 2. Fullerton, M. D., Hakimuddin, F., Bakovic, M. Developmental and metabolic effects of disruption of the mouse CTP:phosphoethanolamine cytidylyltransferase gene (Pcyt2) . Molec. Cell Biol. 27: 3327-3336, 2007. 3. Kaiyrzhanov, R., Wortmann, S., Reid, T., Dehghani, M., Vahidi Mehrjardi, M. Y., Alhaddad, B., Wagner, M., Deschauer, M., Cordts, I., Fernandez-Murray, J. P., Treffer, V., Metanat, Z., Pittman, A., Houlden, H., Meitinger, T., Carroll, C., McMaster, C. R., Maroofian, R. Defective phosphatidylethanolamine biosynthesis leads to a broad ataxia-spasticity spectrum. Brain 144: e30, 2021. Note: Erratum: Brain 144: e52, 2021.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.