Anti-PARG Antibody Picoband®

Boster Bio Anti-PARG Antibody Picoband® catalog # A04301-1. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Poly (ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly (ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

PARG; Poly (ADP-ribose glycohydrolase; EC 3.2.1.143

Gene Name

PARG

Gene ID

8505

UniProt

Q86W56

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PARG recombinant protein (Position: D27-R854) . Human PARG shares 86.5% and 84.7% amino acid (aa) sequence identity with mouse and rat PARG, respectively.

Clonality

Polyclonal

Applications

WB, ICC/IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Ame, J.-C., Apiou, F., Jacobson, E. L., Jacobson, M. K. Assignment of the poly (ADP-ribose) glycohydrolase gene (PARG) to human chromosome 10q11.23 and mouse chromosome 14B by in situ hybridization. Cytogenet. Cell Genet. 85: 269-270, 1999. 2. Andrabi, S. A., Kim, N. S., Yu, S.-W., Wang, H., Koh, D. W., Sasaki, M., Klaus, J. A., Otsuka, T., Zhang, Z., Koehler, R. C., Hurn, P. D., Poirier, G. G., Dawson, V. L., Dawson, T. M. Poly (ADP-ribose) (PAR) polymer is a death signal. Proc. Nat. Acad. Sci. 103: 18308-18313, 2006. 3. Hanai, S., Kanai, M., Ohashi, S., Okamoto, K., Yamada, M., Takahashi, H., Miwa, M. Loss of poly (ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster. Proc. Nat. Acad. Sci. 101: 82-86, 2004.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

111 kDa

Observed Molecular Weight

130 kDa

Applications Notes

Gene Name Synonym

Poly (ADP-ribose) glycohydrolase

Protein Name