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Anti-PAN3 Antibody Picoband® FITC Conjugated

Selected Variant

A05429-1-FITC

Size: 100 µg/Vial

Product Specifications

Background

Contributes to poly (A) -specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly (A) tail shortening. Predicted to act upstream of or within deadenylation-dependent decapping of nuclear-transcribed mRNA; positive regulation of cytoplasmic mRNA processing body assembly; and protein targeting. Part of PAN complex.

Synonyms

PAN3; PAN2-PAN3 deadenylation complex subunit PAN3; PAB1P-dependent poly (A-specific ribonuclease; Poly (A-nuclease deadenylation complex subunit 3; PAN deadenylation complex subunit 3

Gene Name

PAN3

Gene ID

255967

UniProt

Q58A45

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PAN3 recombinant protein (Position: Q227-L887) . Human PAN3 shares 97.4% amino acid (aa) sequence identity with mouse PAN3.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 04/21/2017. 2. Uchida, N., Hoshino, S., Katada, T. Identification of a human cytoplasmic poly (A) nuclease complex stimulated by poly (A) -binding protein. J. Biol. Chem. 279: 1383-1391, 2004.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

96 kDa

Applications Notes

6

Gene Name Synonym

Poly (A) specific ribonuclease subunit PAN3

Protein Name

PAN2-PAN3 deadenylation complex subunit PAN3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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