Anti-PAN3 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
Contributes to poly (A) -specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly (A) tail shortening. Predicted to act upstream of or within deadenylation-dependent decapping of nuclear-transcribed mRNA; positive regulation of cytoplasmic mRNA processing body assembly; and protein targeting. Part of PAN complex.
Synonyms
PAN3; PAN2-PAN3 deadenylation complex subunit PAN3; PAB1P-dependent poly (A-specific ribonuclease; Poly (A-nuclease deadenylation complex subunit 3; PAN deadenylation complex subunit 3
Gene Name
PAN3
Gene ID
255967
UniProt
Q58A45
Host
Rabbit
Reactivity
Human, Mouse
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human PAN3 recombinant protein (Position: Q227-L887) . Human PAN3 shares 97.4% amino acid (aa) sequence identity with mouse PAN3.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Hartz, P. A. Personal Communication. Baltimore, Md. 04/21/2017. 2. Uchida, N., Hoshino, S., Katada, T. Identification of a human cytoplasmic poly (A) nuclease complex stimulated by poly (A) -binding protein. J. Biol. Chem. 279: 1383-1391, 2004.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
96 kDa
Gene Name Synonym
Poly (A) specific ribonuclease subunit PAN3
Protein Name
PAN2-PAN3 deadenylation complex subunit PAN3
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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