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Anti-NPY2R Antibody Picoband® HRP Conjugated

Product Specifications

Background

Predicted to enable calcium channel regulator activity and neuropeptide Y receptor activity. Involved in cardiac left ventricle morphogenesis and outflow tract morphogenesis. Located in cilium. Implicated in Huntington's disease; morbid obesity; and obesity. Biomarker of peripheral artery disease and temporal lobe epilepsy.

Synonyms

NPY2R; Neuropeptide Y receptor type 2; NPY2-R; NPY-Y2 receptor; Y2 receptor

Gene Name

NPY2R

Gene ID

4887

UniProt

P49146

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NPY2R recombinant protein (Position: M1-K367) . Human NPY2R shares 94.8% amino acid (aa) sequence identity with mouse NPY2R.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Ammar, D. A., Eadie, D. M., Wong, D. J., Ma, Y.-Y., Kolakowski, L. F., Jr., Yang-Feng, T. L., Thompson, D. A. Characterization of the human type 2 neuropeptide Y receptor gene (NPY2R) and localization to the chromosome 4q region containing the type 1 neuropeptide Y receptor gene. Genomics 38: 392-398, 1996. 2. Gerald, C., Walker, M. W., Vaysse, P. J.-J., He, C., Branchek, T. A., Weinshank, R. L. Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype. J. Biol. Chem. 270: 26758-26761, 1995. 3. Lovelace, J. W., Ma, J., Yadav, S., Chhabria, K., Shen, H., Pang, Z., Qi, T., Sehgal, R., Zhang, Y., Bali, T., Vaissiere, T., Tan, S., Liu, Y., Rumbaugh, G., Ye, L., Kleinfeld, D., Stringer, C., Augustine, V. Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope. Nature 623: 387-396, 2023.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

43 kDa

Gene Name Synonym

Neuropeptide Y receptor Y2

Protein Name

Neuropeptide Y receptor type 2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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