Anti-NPY2R Antibody Picoband® Biotin Conjugated

Predicted to enable calcium channel regulator activity and neuropeptide Y receptor activity. Involved in cardiac left ventricle morphogenesis and outflow tract morphogenesis. Located in cilium. Implicated in Huntington's disease; morbid obesity; and obesity. Biomarker of peripheral artery disease and temporal lobe epilepsy.

1. Ammar, D. A., Eadie, D. M., Wong, D. J., Ma, Y.-Y., Kolakowski, L. F., Jr., Yang-Feng, T. L., Thompson, D. A. Characterization of the human type 2 neuropeptide Y receptor gene (NPY2R) and localization to the chromosome 4q region containing the type 1 neuropeptide Y receptor gene. Genomics 38: 392-398, 1996. 2. Gerald, C., Walker, M. W., Vaysse, P. J.-J., He, C., Branchek, T. A., Weinshank, R. L. Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype. J. Biol. Chem. 270: 26758-26761, 1995. 3. Lovelace, J. W., Ma, J., Yadav, S., Chhabria, K., Shen, H., Pang, Z., Qi, T., Sehgal, R., Zhang, Y., Bali, T., Vaissiere, T., Tan, S., Liu, Y., Rumbaugh, G., Ye, L., Kleinfeld, D., Stringer, C., Augustine, V. Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope. Nature 623: 387-396, 2023.