Anti-CD42a/GP9 Antibody Picoband®

Involved in blood coagulation and megakaryocyte development. Predicted to be part of glycoprotein Ib-IX-V complex. Is expressed in several structures, including brain; foregut; hemolymphoid system; liver; and male reproductive gland or organ. Human ortholog (s) of this gene implicated in Bernard-Soulier syndrome. Orthologous to human GP9 (glycoprotein IX platelet) .

A synthetic peptide corresponding to a sequence in the middle region of mouse CD42a/GP9. Mouse CD42a/GP9 shares 89.5% amino acid (aa) sequence identity with human CD42a/GP9.

1. Bernard, J., Caen, J., Maroteaux, P. La dystrophie thrombocytaire hemorragipare congenitale. Rev. Hemat. 12: 222-249, 1957. 2. Clemetson, J. M., Kyrle, P. A., Brenner, B., Clemetson, K. J. Variant Bernard-Soulier syndrome associated with a homozygous mutation in the leucine-rich domain of glycoprotein IX. Blood 84: 1124-1131, 1994. 3. Hickey, M. J., Deaven, L. L., Roth, G. J. Human platelet glycoprotein IX: characterization of cDNA and localization of the gene to chromosome 3. FEBS Lett. 274: 189-192, 1990.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.