Anti-NKX2-3 Antibody HRP Conjugated

This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.

A synthetic peptide corresponding to a sequence at the N-terminus of human NKX2-3. Human NKX2-3 shares 75% amino acid (aa) sequence identity with mouse NKX2-3.

1. Harvey, R. P. NK-2 homeobox genes and heart development. Dev. Biol. 178: 203-216, 1996. 2. Pabst, O., Forster, R., Lipp, M., Engel, H., Arnold, H.-H. NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. EMBO J. 19: 2015-2023, 2000. 3. Pabst, O., Schneider, A., Brand, T., Arnold, H.-H. The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development. Dev. Dynamics 209: 29-35, 1997.