Anti-NLGN1 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
Synonyms
NLGN1; KIAA1070; Neuroligin-1
Gene Name
NLGN1
Gene ID
22871
UniProt
Q8N2Q7
Host
Rabbit
Reactivity
Human, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human NLGN1. Human NLGN1 shares 100% amino acid (aa) sequence identity with both mouse and rat NLGN1.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Arac, D., Boucard A. A., Ozkan, E., Strop, P., Newell, E., Sudhof, T. C., Brunger, A. T. Structures of neuroligin-1 and the neuroligin-1/neurexin-1-beta complex reveal specific protein-protein and protein-Ca (2+) interactions. Neuron 56: 992-1003, 2007. 2. Boucard, A. A., Chubykin, A. A., Comoletti, D., Taylor, P., Sudhof, T. C. A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. Neuron 48: 229-236, 2005. 3. Chih, B., Engelman, H., Scheiffele, P. Control of excitatory and inhibitory synapse formation by neuroligins. Science 307: 1324-1328, 2005. Note: Erratum: Science 308: 1413 only, 2005.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
96 kDa
Gene Name Synonym
Neuroligin 1
Protein Name
Neuroligin-1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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