Anti-FHOD1 Antibody Picoband® Biotin Conjugated
Product Specifications
Background
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH) 1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants.
Synonyms
FHOD1; FHOS; FHOS1; FH1/FH2 domain-containing protein 1; Formin homolog overexpressed in spleen 1; FHOS; Formin homology 2 domain-containing protein 1
Gene Name
FHOD1
Gene ID
29109
UniProt
Q9Y613
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human FHOD1 recombinant protein (Position: D290-R1121) . Human FHOD1 shares 82.2% amino acid (aa) sequence identity with mouse FHOD1.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Sanematsu, F., Kanai, A., Ushijima, T., Shiraishi, A., Abe, T., Kage, Y., Sumimoto, H., Takeya, R. Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice. Cytoskeleton 76: 219-229, 2019. 2. Westendorf, J. J., Koka, S. Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics. J. Cell. Biochem. 92: 29-41, 2004. 3. Westendorf, J. J., Mernaugh, R., Hiebert, S. W. Identification and characterization of a protein containing formin homology (FH1/FH2) domains Gene 232: 173-182, 1999.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
127 kDa
Gene Name Synonym
Formin homology 2 domain containing 1
Protein Name
FH1/FH2 domain-containing protein 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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