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Anti-NAGA Antibody Picoband® HRP Conjugated

Product Specifications

Background

NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease) .

Synonyms

NAGA; Alpha-N-acetylgalactosaminidase; EC 3.2.1.49; Alpha-galactosidase B

Gene Name

NAGA

Gene ID

4668

UniProt

P17050

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human NAGA recombinant protein (Position: D43-R329) . Human NAGAshares 86.7% and 85.4% amino acid (aa) sequence identity with mouse and rat NAGA, respectively.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Bakker, H. D., de Sonnaville, M.-L. C. S., Vreken, P., Abeling, N. G. G. M., Groener, J. E. M., Keulemans, J. L. M., van Diggelen, O. P. Human alpha-N-acetylgalactosaminidase (alpha-NAGA) deficiency: no association with neuroaxonal dystrophy? Europ. J. Hum. Genet. 9: 91-96, 2001. 2. Chabas, A., Coll, M. J., Aparicio, M., Rodriguez Diaz, E. Mild phenotypic expression of alpha-N-acetylgalactosaminidase deficiency in two adult siblings. J. Inherit. Metab. Dis. 17: 724-731, 1994. 3. de Groot, P. G., Westerveld, A., Meera Khan, P., Tager, J. M. Localization of a gene for human alpha-galactosidase B (=N-acetyl-alpha-D-galactosaminidase) on chromosome 22. Hum. Genet. 44: 305-312, 1978.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

Calculated Molecular Weight

47 kDa

Gene Name Synonym

Alpha-N-acetylgalactosaminidase

Protein Name

Alpha-N-acetylgalactosaminidase

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.

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