Anti-NAGA Antibody Picoband® Biotin Conjugated
Product Specifications
Background
NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease) .
Synonyms
NAGA; Alpha-N-acetylgalactosaminidase; EC 3.2.1.49; Alpha-galactosidase B
Gene Name
NAGA
Gene ID
4668
UniProt
P17050
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human NAGA recombinant protein (Position: D43-R329) . Human NAGAshares 86.7% and 85.4% amino acid (aa) sequence identity with mouse and rat NAGA, respectively.
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Bakker, H. D., de Sonnaville, M.-L. C. S., Vreken, P., Abeling, N. G. G. M., Groener, J. E. M., Keulemans, J. L. M., van Diggelen, O. P. Human alpha-N-acetylgalactosaminidase (alpha-NAGA) deficiency: no association with neuroaxonal dystrophy? Europ. J. Hum. Genet. 9: 91-96, 2001. 2. Chabas, A., Coll, M. J., Aparicio, M., Rodriguez Diaz, E. Mild phenotypic expression of alpha-N-acetylgalactosaminidase deficiency in two adult siblings. J. Inherit. Metab. Dis. 17: 724-731, 1994. 3. de Groot, P. G., Westerveld, A., Meera Khan, P., Tager, J. M. Localization of a gene for human alpha-galactosidase B (=N-acetyl-alpha-D-galactosaminidase) on chromosome 22. Hum. Genet. 44: 305-312, 1978.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.
Calculated Molecular Weight
47 kDa
Gene Name Synonym
Alpha-N-acetylgalactosaminidase
Protein Name
Alpha-N-acetylgalactosaminidase
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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